Profilo vs Rejuran: Which Is The Best Treatment for you

October 15, 2021

Profilo vs Rejuran: Which Is The Best Treatment for you

Table Of Contents

Ever looked back at pictures of your younger self with nostalgia, reminiscing over the days when your skin was smooth, supple, and wrinkle-free? What if we told you that reversing the signs of ageing on your skin has never been easier? While plastic surgery and fillers used to lead in the day, cosmetic treatment has since advanced by leaps and bounds to work at naturally reversing signs of ageing through popular treatments such as Rejuran Healer and Profilo.


But which among these treatments is superior compared to the other and which should you opt for?

In this article, we take you through some essential information on injectables, including debunking myths associated with them, and determining the more ‘powerful’ treatment among the two.

And so, let the Rejuran Healer vs Profilo battle begin!

Before we delve any deeper, it is first important to understand the basics of these injectables so that you can gain a better understanding of their treatments.

What Are Anti-Aging Injections?

Once we pass our 30s, our body starts to naturally decline the production of hyaluronic acid, elastin, and collagen. These essential components are what keeps our skin looking firm, bouncy, and healthy during our teens and early 20s. This is when you will eventually start to notice fine lines, dry, saggy, dull skin, and enlarged pores with every passing year.

Anti-ageing injections contain special, potent solutions used in cosmetic treatments to slow down and even reverse the signs of ageing. They work by supplementing the skin with these nutrients to better promote skin health and rejuvenation. With each use of these injectables, you will notice plumper, firmer skin with reduced wrinkles and dehydration. With their easy accessibility and effective results, it’s no wonder requests for these treatments alone have peaked at 4 million in 2019 – and this is excluding recipients of the treatment not located in the USA.

What is Profhilo?


A more newly introduced treatment compared to Rejuran Healer, Profilo is an anti-ageing injection that increases the firmness and hydration of your skin by boosting its collagen and elastin production.

Made up mainly of hyaluronic acid, which is naturally produced by our body, the primary function of this treatment is to keep the skin moisturized, elastic, and continue collagen production that would have reduced as a result of ageing.

This slows down visible signs of ageing by repairing damaged skin cells and increasing its regeneration to reveal younger and plumper skin.

How does Profhilo work?


Following your consultation sessions, our medical advisors will begin the procedure by first applying a numbing cream to your face.

Injecting Profhilo requires the Bio Aesthetic Point (BAP) technique, which involves administering a sequence of 5 strategically placed injections on either side of the face. This accumulates to 10 overall injection points that will be marked prior to your treatment commencement.

This technique was specifically developed for Profilo using CT scanning in order to determine facial tissue placement and ideal injection sites. The solution will then be injected into these points to allow natural, uniform spreading via muscle movements. This allows the solution to hydrate the cells, so your skin can regain its youthful appearance.

When Can I Expect Results?

You should be able to see full results within 4-6 weeks as it takes some time for collagen and elastin production to be visible. You will however notice some reduction in the wrinkles and appearances of saggy skin.

To maximize cell regeneration benefits and produce better results, we recommend an additional two treatment sessions – each with a month’s interval.

Maintenance injections every 6 to 9 months would allow you to stay ahead of the ageing and cell turnover processes.

What Is Rejuran Healer?


Rejuran is an injectable that focuses on skin repair and rejuvenation to counter the ageing process. Made from salmon DNA fragments called polynucleotides (PDRN) which closely match our DNA, Rejuran Healer promotes the initiation of skin repair and healing starting from the cell itself. As such, this treatment induces cell growth and activity of dermal fibroblasts to produce skin loving proteins as well as molecules like collagen, glycosaminoglycans, and hyaluronic acid for a young, “baby-like” appearance.

This clinically proven biocompatible solution will also encourage a reduction in acne scars and large pores while strengthening the skin barrier to increase protection against harmful environmental substances that eventually causes premature ageing. This means that Rejuran Healer is not only capable of naturally reversing the effects of ageing, it also acts as a prevention to potential environmental effects that may harm your skin’s health or vitality – a two in one treatment.

How does Rejuran Healer work?

Similar to Profilo, Rejuran Healer is administered via ultra-fine needles following the application of a numbing cream. The solution can be injected either with a gun or manually, depending on your skin’s condition.

Unlike Profilo however, Rejuran Healer is not limited to specific areas and includes the forehead, chin, upper lip, nose and even your delicate under eye area where pressing as well as common concerns like crow’s feet lines can be targeted. This remains to be the reason why Rejuran Healer sessions are both longer and require multiple injections.

When Can I Expect Results?


Rejuran Healer effects are visible with as little as one session. Your skin will feel softer and take on a bouncier appearance as hydration levels improve and skin dermis as well as epidermis layers thicken. You will also notice a significant difference in pore sizes and acne scars as they respectively tighten and disappear.

For most cases, we advise you to attend at least 4 sessions, each 3 weeks apart, to get the best out of every Rejuran Healer treatment. This includes a 6-month maintenance session to preserve your newly improved skin health, elasticity, and glow.

Are There Any Side Effects?

Both these treatments are backed by multiple researches and clinically proven results to ensure little to no side effects are unearthed following each session or complete procedure. This includes taking precautions to purify the acquired Salmon DNA so that the administered solution is free of unnecessary immunogenic proteins that may trigger adverse immune responses.

Any tiny bruising or swelling as a result of the injections are no need for alarm and will quickly subside within 24 to 48 hours.

Common Myths on Injectables


Those new to the world of injectables often hold certain misconceptions about the treatment. Here we address the most commonly believed concerns on anti-ageing injections;

Myth #1: “Injectables make you seem like you had plastic surgery – it looks unnatural”.

Contrary to popular belief, these treatments centre on naturally rejuvenating your skin from within to rewind the effect of time, pollution, and UV exposure, leaving behind younger, tighter skin. Unlike fillers or surgeries, no physical adjustments will be made to your face. Instead, what you get is a radiant, more youthful appearance that is entirely natural without going under the knife.

Myth#2: “Injecting your face is dangerous.”

Injectable solutions undergo stringent clinical tests to ensure the compounds and ingredients used are biocompatible as well as safely administered, leaving behind little to no side effects.

While there may be slight discomfort as the solutions are being injected into your face, measures such as the usage of fine, thin needles along with the application of some numbing cream will help to alleviate any pain you may experience.

Myth#3: “Injectables can be administered in any facial salon.”

It is important to take into account the medical background of both the individual handling the procedure as well as the medical wellness company you choose to make an appointment with.

Make sure to carefully select from options where your medical advisors hold necessary accreditations in varying aesthetic procedures and hail from medically recognised institutions. This would ensure that your safety and comfort remain top priorities at all times.

Myth#4: “Only those with matured skin opt for injectables.”

While these treatments help reduce the appearances of fine lines as well as wrinkles, the effects of Rejuran and Profilo are not merely limited to treating these concerns.

From boosting skin hydration, to improving acne scarring, dark eye circles, dull skin, stretch marks, and pore reduction, you can reap the benefits of these injectables in more ways than one.

Now that we have debunked the more pressing myths associated with injectables, how do you decide on which treatment to opt for?

Which One Is More Suitable For Me?

At first glance, the effects of Rejuran Healer and Profilo appear somewhat similar as both the treatments are able to achieve the following results:

  • Anti-ageing via skin regeneration (E.g., reduced wrinkles, fine lines, and saggy skin)
  • Skin rejuvenation
  • Improved hydration

But this is where their similarities end. From the type of active ingredients used (Hyaluronic Acid and Salmon DNA), to the way they act on your skin, and its resultant effects, both these injectables differ significantly from one another.

While opting for Profilo can encourage bio-remodelling, requires lesser treatment sessions, and a longer duration of efficacy, it is unable to target wider areas of concern. Beyond improving fine lines and wrinkles, this treatment is limited in its effects.

However, Rejuran Healer is able to not only address similar issues, but also repair severely damaged skin, acne scarring, pigmentation, minimize enlarged pores, improve skin texture, regulate skin oily skin, and enhance skin barrier for better protection against harmful environmental stimuli.

Since BAP injection sites are restricted to five points which includes only the middle and lower face, this narrows down treatable areas to exclude spots like your brow, under eye, and forehead that often show tell-tale signs of ageing. It is also great for those who have dry skin, dark circles, or conditions such as eczema.

Rejuran Healer treatments are also best suited for people of all ages – starting from those in their 20s and above while Profilo is only recommended for people aged between their 30s and 40s.

In conclusion, by opting for Rejuran Healer treatments, you can reap better benefits at a more budget friendly price point. This however does not mean that Profilo is any less effective. Feel free to slowly work your way up toward this treatment or opt for it if you have room to splurge. Nonetheless, be sure to also consult your medical advisors as each of these treatments hold varying levels of suitability based on your skin’s unique type, need, and concern.

Profhilo Rejuran Healer
Main components Hyaluronic acid Polynucleotides made from salmon DNA
Uses Skin hydration
Increased collagen and elastin production
Bio-remodeling of the skin
Skin repair
Increased collagen production
Who is it suitable for? Age 30-40s
Dry skin and sagging
20 and above
Acne scars or skin pigmentation
Large pores
Dull skin
Injection method BAP technique Manually or injection gun
Recommend number of treatments 2 sessions, 1 month part 1 session every 6-9 months for maintenance 4 sessions, 3 weeks apart 1 session every 6 months for maintenance
How long do results last? Up to 6 months Up to 6 months
Pricing (per session) $1000 $298

Can I Combine Both Treatments?

Of course, you can! Rejuran Healer and Profilo can definitely be combined for a more holistic treatment package. In fact, considering the different mechanisms of the treatments, their synergistic effects could prove desirable. Do note that you should schedule the sessions with a month’s interval and consult a medical professional beforehand.

So, be sure to get in touch with our medical advisors to form a treatment plan that is catered specifically for you.

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